It was more than the fans who noticed when Yankee shortstop Gleyber Torres didn’t come out on the field during a game in early May against the Tampa Bay Rays. The world tuned in when Torres became the eighth person in the Yankee organization to test positive for coronavirus despite being fully vaccinated. Known as “positive advances,” these and other cases have become a source of confusion for many vaccinated and unvaccinated individuals.
According to the Centers for Disease Control and Prevention (CDC), advanced cases occur when a fully vaccinated person gets the virus. Often caused by strong immune responses to the vaccine or by variants of the virus, most advanced cases go unnoticed without symptoms. As of May 10, 2021, of the more than 131 million people in the United States completely vaccinated, only 1,359 had been hospitalized or had a fatal progression case. [Note: 342 of 1,136 hospitalizations reported as asymptomatic or not related to Covid-19 and 42 of 223 fatal cases reported as asymptomatic or not related to Covid-19.]
“That’s less than .0001 percent,” clarifies Amesh Adalja, MD, a senior academic at the Johns Hopkins Center for Health Safety Bloomberg School of Public Health, “It’s a decimal point with four zeros … and then a number. It’s not quite low, the probability is almost nil, there has never been a 100% effective vaccine, so we always expect a certain number of advances in any vaccine.If people say that .00001 means it doesn’t work “I think they really have a poor understanding of math or science. It’s pretty nil, so innovative infections are negligible.”
Like many other vaccines, the biggest benefit of the Covid-19 vaccine is not that it prevents infection, but that it prevents serious illness, hospitalization, and death; and, in 99.9999 percent of cases, that’s exactly what you’re doing.
“Vaccines work clearly, with some of the highest efficacy rates for any vaccine on the market today,” says Dr. Jesse Erasmus, a microbiology researcher and virologist at the Fuller Lab at the University of Washington School of Medicine. who is also working on a second-generation Covid-19 vaccine candidate. “An ideal vaccine would protect against infections and disease, and there is evidence that these vaccines do both, but they are definitely more effective in protecting them from disease than in preventing them. The major disease is extremely rare, without detect any serious illness in vaccinated people. Most likely they will occur in immunocompromised individuals or in people with a weakened immune system. “
There is currently no good way to know exactly what immune response power a person had when receiving the Covid-19 vaccine, that is, it is not a question of whether a person felt side effects after the first or second dose or not, but the likelihood is high that healthy, fully vaccinated people who do not take immune-suppressing medications can safely return to normal life.
“Symptoms may mean a strong immune response, but the absence of symptoms does not prevent a strong immune response,” Dr. Adalja explains. “We don’t have enough data to be able to tell when advanced infections occur if there is a certain risk factor such as age or gender, but based solely on other vaccines, it is likely that people who have a strong response to vaccine are elderly people or people taking immunosuppressive drugs “.
Fortunately, advanced infections are associated with such a low viral load that they are not even contagious to others and most cases are only diagnosed due to periodic testing requirements, which is what happened in all eight cases of viral infections. Yankees.
“When we look at these advanced infections, the vast majority of these infections show no symptoms, so they are not even clinically significant,” Dr. Adalja adds. His opinion: “If you are completely vaccinated and if you do not have any other medical problems, not only would I not worry about advanced infections, but even if you are immunocompromised and have an advanced infection, the likelihood of this advanced infection as well it is insignificant to be severe enough to cause symptoms. ”
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