Sarah Gilbert, a professor of vaccinology at Oxford University who carried out initial research into the AstraZeneca Plc vaccine, told the BBC that “efforts are being made to develop a new generation of vaccines to redirect protection to emerging variants as puncture reinforcement, if it is necessary to do so ”. Pfizer Inc. and its German partner BioNTech SE, as well as Moderna Inc., have said their results indicate that their vaccines should still work against the strain detected in South Africa, despite the reduced potency. Moderna later announced that its Covid-19 reinforcement shots gave positive results against this strain, as well as against the P.1 variant, according to the first results of a mid-phase trial. Pfizer and Novovax have also said they are working on a reinforcement or combined shot. These alterations are not unheard of: it occurs annually with seasonal flu, which is evolving rapidly. Unlike influenza, coronaviruses have a genetic mechanism of self-correction that minimizes mutations.